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two halves of a pot roast sandwich on a cutting board
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Best Pot Roast Sandwich

My Pot Roast Sandwich Recipe puts those pot roast leftovers to scrumptious use. Piled high with tender, slow-cooked pot roast, caramelized onions, and melty American cheese and toasted to perfection!
Course Main Course
Cuisine American
Keyword pot roast sandwich
Prep Time 2 minutes
Cook Time 8 minutes
Total Time 10 minutes
Servings 1 sandwich
Calories 539kcal

Equipment

Ingredients

  • 1 cup leftover pot roast I used Mississippi pot roast
  • 2 slices bread
  • 3 slices cheese I used American cheese
  • cup caramelized onions
  • butter for spreading on bread
  • 1 Tablespoon grated parmesan cheese

Instructions

  • Begin by buttering one slide of each piece of bread. Evenly sprinkle parmesan cheese on top.
    2 slices bread, butter, 1 Tablespoon grated parmesan cheese
    spreading butter and parmesan cheese on a slice on bread for a pot roast sandwich
  • Flip one piece over. Layer 2 slices of cheese on the bread. Next, layer your leftover pot roast on top of the cheese slices.
    1 cup leftover pot roast, 3 slices cheese
    topping a slice of bread with American cheese and pot roast
  • Top with another slice of cheese, then layer with caramelized onions.
    3 slices cheese, ⅓ cup caramelized onions
    adding more cheese and sautéed onions to a slice of bread
  • Top with your other slice of bread, butter side up.
    2 slices bread
    topping pot roast sandwich with another piece of bread topped with butter and parmesan cheese
  • Place in the air fryer at 350°F for 5 minutes on one side.
    pot roast sandwich in the air fryer
  • After 5 minutes, flip and cook an additional 4 minutes, or until golden brown. Serve and enjoy!
    cooked pot roast sandwich in the air fryer

Video

Notes

  • Find the perfect bread: I love serving my pot roast sandwiches on hard, crusty bread.
  • Try out a different cheese: Mix up the flavors and try out a different cheese like pepper jack cheese, or mozzarella cheese.
  • Add more vegetables: Like mushrooms, or add some peppers onto your sandwich!
  • Don't forget about the au jus: Add a few spoonfuls of leftover au jus on top of your sandwich to add extra moisture to the sandwich.
Skillet instructions:
  • You can also use a pain to cook these pot roast sandwiches: heat a skillet over medium-low heat and cook for 5 minutes on one side. Flip and cook for an additional 5-6 minutes, or until golden brown.

Nutrition

Serving: 1sandwich | Calories: 539kcal | Carbohydrates: 34g | Protein: 28g | Fat: 33g | Saturated Fat: 17g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 7g | Trans Fat: 0.02g | Cholesterol: 88mg | Sodium: 904mg | Potassium: 231mg | Fiber: 3g | Sugar: 6g | Vitamin A: 887IU | Vitamin C: 4mg | Calcium: 720mg | Iron: 2mg